A drone strike believed to be executed by US forces targeting a truck carrying weapons from Iraq to Syria, has left two men wounded.

The Syrian Observatory for Human Rights claim the injured were identified as non-Syrian militia members affiliated with Iran, and were hospitalized. 

The attack took place on the road between Al-Ghabra city and Al-Hamdan Airport in the eastern countryside of Deir Ezzor after the truck crossed the Iraqi-Syrian border.

It follows action taken by Jordan on Friday, when airstrikes were launched on warehouses and hideouts linked to Iran-associated drug and weapons smuggling networks in Syria.

Jordanian officials, like Western allies, attribute the rise in smuggling activities to the influence of Lebanon's Iran-backed Hezbollah group and other pro-Iranian militias in southern Syria.

UN experts, along with US and European officials, contend that the illicit drug trade is financing pro-Iranian militias and paramilitary forces, a consequence of more than a decade of conflict in Syria.